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A design of experiments approach was used to optimize the plga nanoparticles to have the maximum quercetin loading, optimal cationic charge, and folic acid coating. We showed that quercetin reduced pulmonary fibrosis and inhibited extracellular matrix (ecm) formation. These nanoparticles offer a unique approach to enhancing delivery. In this study, we employed plga nanoparticles to prepare nanoparticles encapsulated with.
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This article aims to develop. The utilization of quercetin nanoparticles as a novel therapeutic strategy has garnered significant attention in recent years. Plga degradatio rate depends on its molecular weight and on the molar ratio of the two monomer. Quercetin also attenuated macrophage senescence induced by sio 2.
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Administration of plga nanoparticles is associated with a minimal systemic toxicity [2,9].